06 May 2019
Active ingredient: Citalopram (citalopram)
- Pram - Lannacher Heilmittel GmbH / Omega Pharma (Austria / Russia)
- Siozam - Veropharm
- Cipramil - Lundbek AS (Denmark)
- Zitalek - Zentiva a.s. (Czech Republic)
- Citalopram hydrobromide - Industriale Chimica S.r.L. (Italy)
- Citalanol - MASTERLEC JSC (Russia)
- Cytol - Abdi Ibrahim Ilac San. ve Tic. A.S. (Turkey)
- Celexa - Forest Laboratories, Inc. (U.S.A. and Canada)
Different drugs contain citalopram in different countries: Cipramil (Russia, Australia, Brazil, Finland, Germany, Netherlands, Ireland, Israel, Norway, Sweden, Great Britain, New Zealand, South Africa), Elopram (Italy), Citol, Vodelax (Turkey ), Citrol, Seropram, Talam (Europe and Australia), Citabax, Citaxin (Poland), Citalec (Slovakia, Czech Republic), Recital (Israel, manufactured by Thrima Inc. for Unipharm Ltd.), Zetalo (India), Celapram, Ciazil Austria, New Zealand), Zentius, Cimal (South America), Ciprapine (Ireland), Cilift (South Africa), Citox (Mexico), Temperax (Chile, Peru, Argentina), Talohexal, Citopam (Australia), Akarin (Denmark), Cipram (Turkey, Denmark, producer H. Lundbeck A / S), Dalsan (Eastern Europe), Pramcit (Pakistan), Celius (Greece), Humorup (Argentina), Oropram (Iceland, producer of Actavis).
Citalopram is an antidepressant included in the group of selective serotonin reuptake inhibitors (SSRIs). At the same time, citalopram practically does not bind to the majority of receptors and does not affect the work of enzymes. It does not have a noticeable effect on the cardiovascular system, it does not provoke weight gain, does not affect the appetite and does not interfere with the work of the kidneys and liver. Citalopram does not inhibit the cognitive function of a person, it does not have the effect of drowsiness. In addition, there was no negative effect of the drug on reproductive function. Citalopram is a fat-soluble compound, and therefore it is absorbed very quickly by the body and begins to act after a minimum time after administration. The antidepressant is not addictive. Compatible with many other drugs, including analgesics, antihistamines and antihypertensive drugs. An important advantage of the drug is its tolerability by most people of all ages. A distinct antidepressant effect occurs after 2-4 weeks of citalopram, starting to manifest itself at the end of the first week. The percentage of patients who experienced improvement as a result of the drug treatment (according to a variety of studies) is about 80 people out of a hundred. According to two Russian studies conducted in the years 98-99, citalopram has not only a proper antidepressant effect, but also a pronounced anti-anxiety, and it is virtually equally effective under conditions of any severity. In addition, with citalopram treatment, there is virtually no withdrawal syndrome.
Indications for use: Treatment and prevention of depression of any origin; treatment of panic disorders, both with fear of open space, and without it; treatment of obsessive-compulsive disorder (OCD).
Dosage and administration: Citalopram is taken orally once a day during a meal or on an empty stomach. It is recommended to start treatment with depressions at a dosage of 20 mg / day. Depending on the individual reaction of the patient's body, the dose can be increased to a maximum (60 mg / day).
In the treatment of panic disorders, the minimum recommended dose is 10 mg / day for the first week and 20 mg / day for the second and subsequent weeks of treatment. In addition, if necessary, it is possible to gradually increase the daily dose to 60 mg.
The recommended dosage for OCD is 20 mg of citalopram per day. The dose can be gradually increased by 20 mg / day until an adequate therapeutic effect is obtained. The maximum daily dose is 60 mg.
For elderly patients (from 65 years old) the maximum dose of citalopram is 40 mg / day. Patients with impaired liver function should limit the intake of the drug to 30 mg per day. If there are abnormalities in the work of the kidneys, citalopram is allowed without any restrictions. However, this applies only to minor and moderate violations. There is no information on the effects of citalopram in severe renal failure.
Contraindications: Hypersensitivity to the components of the drug, in particular, to citalopram itself, pregnancy and lactation. In addition, simultaneous treatment with citalopram and MAO inhibitors is prohibited (at least 2 weeks, or a week after completion of citalopram treatment) after the completion of the course of taking MAO inhibitors. Caitralopram should be taken with caution in patients with impaired hepatic or renal function.
Side effects: The drug is not likely to cause side effects. There are very few: fatigue, drowsiness or, on the contrary, insomnia, anxiety, mood swings, euphoria, dry mouth, nausea, abdominal pain, vomiting, heart rhythm disturbance, taste disturbance. There is a possibility of allergic reactions, such as a skin rash or itching.
Storage conditions: Store the drug as far from children's eyes as possible at a temperature of no higher than 25 ° C.
Terms of selling from the pharmacy: Without a prescription.