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Dexa-Gentamicin (Dexa-Gentamycin) eye drops - is a combined preparation used in ophthalmology, the components of which have antimicrobial and anti-inflammatory effects. It is used mainly for eye infections caused by gentamicin-sensitive bacteria, also for allergic reactions and in the postoperative period.
Combination drug for topical application in ophthalmology.
The drug provides a sufficient dose and compatibility of both active components, as well as reduces the likelihood of error in the selection of a dose in the case of a separate designation of the components included in the preparation.
Gentamicin is a water-soluble antibiotic of the aminoglycoside group. It has bactericidal action against a wide range of gram-positive and gram-negative bacteria. Gentamicin does not penetrate through the intact cornea. Damage and inflammation of the cornea lead to the penetration of gentamicin through the cornea into the anterior chamber of the eye 15 minutes after instillation of eye drops or ophthalmic ointment.
Dexamethasone is a synthetic SCS, whose anti-inflammatory and antiallergic effect is 25 times greater than the action of cortisol, which is a natural endogenous SCS. Possible penetration of dexamethasone through the cornea with intact epithelium into the moisture of the anterior chamber of the eye; However, in the case of an inflammatory process or epithelial damage, the rate of penetration of dexamethasone through the cornea significantly increases.
With topical application, systemic absorption is low.
If the use of contact lenses is necessary, then they should be removed before using Dexa-Gentamicin and re-established no earlier than 20 minutes.
The patient should be informed that if side effects occur, the treatment should be stopped immediately and referred to the ophthalmologist.
Use in Pediatrics
To date, clinical trials of the safety and efficacy of the use of the Dexa-Gentamicin drug in children are not available. The use of the drug in pediatrics is possible if the expected therapeutic effect exceeds the potential risk of side effects.
Impact on the ability to drive vehicles and manage mechanisms
Immediately after the use of the drug Dexa-Gentamycin, a short-term disturbance of visual acuity may occur, leading to a slowing down of psychomotor reactions. Therefore, it is not recommended to apply the drug directly before working with mechanisms and driving vehicles.
Eye drops Dexa-Gentamycin is instilled in the conjunctival sac by 1-2 drops 4-6 times a day.
The duration of treatment with eye drops Dexa-Gentamicin usually does not exceed 2-3 weeks.
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