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Dorzopt eye drops 2% 5ml

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Dorzopt (Dorsopt) eye drops - a drug for the treatment of glaucoma, which reduces the increased intraocular pressure. Refers to inhibitors of carbonic anhydrase. Does not cause a narrowing of the pupil, spasm of accommodation, visual disturbances in bright light.

Dorzopt eye drops - antiglaucoma preparation, a local inhibitor of carbonic anhydrase. Reduces the secretion of the aqueous humor, slowing the formation of bicarbonate, followed by a weakening of the transfer of sodium and water. Does not cause a spasm of accommodation, miosis, gemeralopia.

Pharmacokinetics

Suction

It penetrates the eye mainly through the cornea (to a lesser extent through the sclera or limbus). Systemic absorption is low. After entering the blood quickly penetrates into the red blood cells containing a significant amount of carbonic anhydrase II.

Distribution and Metabolism

Binding to plasma proteins - 33%. It is transformed into an N-desethylated metabolite, less active with respect to carbonic anhydrase II, but capable of blocking carbonic anhydrase I. For long-term use, it accumulates in red blood cells.

Excretion

It is excreted by the kidneys in the unmodified form and in the form of metabolites. After cancellation, the rapid phase of withdrawal is replaced by a slow one, caused by the gradual release of the drug from erythrocytes, with T1 / 2 about 4 months.

Indications:

  • Open angle (including secondary) glaucoma;
  • pseudoexfoliation glaucoma;
  • ophthalmohypertension.

Contraindications:

  • Hypersensitivity to any component of the drug;
  • chronic renal failure (QC less than 30 ml / min);
  • hyperchloremic acidosis;
  • children and adolescents under 18;
  • pregnancy;
  • lactation period (breastfeeding);
  • simultaneous oral administration of inhibitors of carbonic anhydrase.

With caution: prescribe the drug for diabetes, liver failure, corneal diseases, use in patients after antiglaukomatoznyh operations (risk of eye hypotension, retinal detachment).

Special instructions:

The preservative of benzalkonium chloride contained in the preparation can be adsorbed by soft contact lenses, causing eye irritation and toxic effects. The drug is used only after removal of contact lenses. To establish contact lenses should be no earlier than 15 minutes after instillation.

It is necessary to control the content of potassium, electrolytes in the blood serum and its pH.

In elderly patients, sensitivity to dorsolimide may increase, so this category of patients may require a dose reduction.

Impact on the ability to drive vehicles and other mechanisms that require increased concentration

During the treatment period, care must be taken when driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Suggested Use:

Bury 1 drop in the conjunctival sac of the affected eye 3 times / day. In combination with beta-blockers for topical administration - 1 drop 2 times / day. If several local ophthalmic preparations are used in the treatment, they are administered at an interval of 10 minutes.

Packaging:

  • Comes in original packaging. Item is brand new and unopened.

Storage:

  • Keep away from direct sunlight.
  • Keep locked and away from children.
  • Store in dry place at room temperature.
  • Do not exceed storage temperature higher than 25 C

Important notice- the outer box design may vary before prior notice!

 

Dorzopt eye drops 2% 5ml buy treatment of glaucoma online

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