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Xantinol nicotinate (Xantinoli nicotinatis) - a means of improving the microcirculation; It combines the properties of theophylline and nicotinic acid. It is the expansion of peripheral blood vessels, improves the collateral circulation, improves microcirculation, improves oxygenation and nutrition of tissues. Has antiplatelet effect, it activates fibrinolysis, improves cerebral blood circulation, reduces blood viscosity.
It increases oxidative phosphorylation and ATP synthesis. By blocking the adenosine receptors and PDE increases the concentration of cAMP in the cell stimulates the synthesis of substrate NAD and NADP.
By reducing the total peripheral vascular resistance and increasing the myocardial contraction, increases cardiac output and increased cerebral blood flow, reduces the severity of the consequences of cerebral hypoxia.
It causes nikotinopodobny syndrome accompanied by hyperesthesia of the mucous membrane of the nasal cavity and mouth: sharpens the olfactory and taste sensitivity. In this regard, the smell and taste of the proposed reaction during nikotinopodobnoy alcoholic beverages and foods perceived more sharp and unpleasant.
Prolonged use has an anti-atherosclerotic effect, activates fibrinolysis processes, reduces the concentration of cholesterol and atherogenic lipids, increases the activity of lipoprotein lipase, reduces blood viscosity, reduces platelet aggregation.
Occlusive disease, atherosclerosis of the lower extremities, intermittent claudication, Raynaud's disease, diabetic angiopathy, arterial thrombosis, retinopathy, trophic ulcers of the lower extremities, atherosclerotic cerebrovascular accidents, migraines, Meniere's syndrome, dermatitis, acute thrombophlebitis of superficial and deep veins.
Bleeding, myocardial infarction, congestive heart failure, gastric ulcer and duodenal ulcers, the first trimester of pregnancy.
To use caution when labile blood pressure.
To use caution in conjunction with antihypertensive drugs.
Effects on ability to drive vehicles and management mechanisms
With special care to apply for drivers of vehicles, as well as in patients involved in potentially hazardous activities.
Inside, the food is not liquid, - 1 (2-4 if necessary) the tablet three times a day for two months.
Since the cardiovascular system: possible decrease in blood pressure, transient feeling of warmth, redness of the skin.
From the digestive system: rarely - nausea, diarrhea, anorexia, gastralgia; long-term use at high doses may increase the levels of transaminases and alkaline phosphatase.
Other: weakness, dizziness; long-term use in high doses may change glucose tolerance, increased uric acid levels in serum.
In an application with drugs, has a hypotensive effect (beta-blockers, ergot alkaloids, alpha-blockers, sympatholytic, ganglioplegic), with strofantinom possible sharp increase in their actions.
Important notice- the outer box design may vary before prior notice!
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